There was no obvious reason why the plane went down. Capt. Benoit Zeisser of the Digne-le-Bains police said there were some clouds in the region but the cloud ceiling was not low and there did not appear to be turbulence.
In addition, the safest part of a flight is when the plane is at cruising elevation. Just 10 percent of fatal accidents occur at that point, according to a safety analysis by Boeing. In contrast, takeoff and the initial climb accounts for 14 percent of crashes and final approach and landing accounts for 47 percent.
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The A320 plane is a workhorse of modern aviation. Similar to the Boeing 737, the single-aisle, twin-engine jet is used to connect cities between one and five hours apart. Worldwide, 3,606 A320s are in operation, according to Airbus.
The A320 is certified to fly up to 39,000 feet but it can begin to experience problems as low as 37,000 feet, depending on temperature and weight, including fuel, cargo and passengers.
The A320 family also has a good safety record, with just 0.14 fatal accidents per million takeoffs, according to a Boeing safety analysis. In a live briefing Tuesday, French President Francis Hollande said it was likely that a number of the victims were German. He said it was not clear whether anyone on the ground had been injured by the crash. "It's a tragedy on our soil," he said.
The last time a passenger jet crashed in France was the 2000 Concorde accident, which left 113 dead — 109 in the plane and four on the ground.
Later Hollande spoke with German Chancellor Angela Merkel to express his condolences. Merkel was "deeply shocked" by the crash and cancelled all other appointments for the day, her spokesman said.