KATHMANDU, Feb 3: After former US president George Bush, it was Chinese premier Wen Jiabao who was hit with a shoe, agencies reported.
A protester threw a shoe at during a speech at Cambridge University and called the Chinese prime minister a "dictator", BBC said.
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The shoe landed about a metre away from Wen and the protester, a young man, was then removed by security guards.
Wen, who earlier signed a series of trade agreements with Gordon Brown on the final day of a three-day UK visit, described the incident as "despicable".
Protests have taken place about human rights and Tibet during his visit.