In Jumla, the police had to baton-charge a group of protesters who took to the streets defying a curfew imposed the District Administration Office. Six protesters were injured in the police action.
In Khalanga, the district headquarters, the police fire three rounds in the air to disperse demonstrators, even as protests raged unabated in other parts of Karnali zone incliding in Humla, Dolpa, Mugu and Kalikot districts.
Security personnel intervened after agitators started vandalizing local offices and tearing down official signboards, said officials.
The agitators replaced the existing signboards with the ones that read the offices were under "Karnali Province."
Among those injured in the clashes, two are said to be in serious condition.
"The police showed their brutality against the Jumla residents," said Yogi, former district secretary of the CPN-UML. Last Friday alone, 13 people were injured when the police intervened in the protest.
Human rights activists have expressed concern over what they have described as excessive use of force by security personnel.
Local civil society organizations have sought to portray the protests as a fight for the welfare of the people of Karnali zone who have faced injustice and discrimination from the state since a long time.
Agitators have flocked to the district headquarters, Khalanga, to pile pressure on the government authority to fulfill their demands.
Meanwhile, Jumla's Chief District Officer Dipendra Raj Poudel claimed that the situation has been brought under control with security personnel deployed at all the sites where demonstrators have gathered to call for an undivided Karnali as a separate province with special power.
Meanwhile, the official signboards of local offices in the district headquarters were restored later on the day.
The residents, local political parties and civil society leaders have raised one voice against the political parties' decision to keep Karnali region in with far western region in carving up province no. 6.
In Rukum, the protesters have relented after leaders hinted at reviewing the decision to divide the district into two parts. Instead of all day long shutdowns, those pressing for undivided Rukum said, the closure would be enforced from 12 to 3 in the afternoon
Meanwhile in Surkhet, the family of three, who died last week after sustaining serious injuries in police intervention during the protests demanding undivided mid-west, received the bodies on Monday.
The families accepted the bodies after the government agreed to provide each with Rs 1 million and declare the deceased as martyr.
Protests demanding undivided Karnali continue

Agriculture Research Council building set on fire by protestors.