Hamilton Masakadza is leading Zimbabwe after regular captain Elton Chigumbura was suspended for the remaining two matches of the series after a slow over rate during his side's 41-run loss in the first ODI.
In four changes for Zimbabwe, Chamu Chibhabha replaced Chigumbura while Charles Coventry came in for Craig Ervine, who has injured his hamstring. Prosper Utseya, who is ill, made way for Tawanda Mupariwa and Graeme Cremer replaced dropped fast bowler Christopher Mpofu.
Pakistan kept the same team from Tuesday's match.
Zimbabwe is the first international team to tour Pakistan since 2009 when gunmen attacked Sri Lanka's team bus in Lahore.
Related story
Pakistan wins toss, will bowl 1st against England
